Author

C. Bishop

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 4 Cell Biology· 2 Ecology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 11 Organism:human· 7 Research Focus:cell type annotation· 6 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 5 Assay:proteomics· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2

Frequent Co-Authors

A. Suhrbier· 5 shared D. J. Rawle· 4 shared T. Dumenil· 4 shared B. Tang· 3 shared K. Yan· 3 shared J. Spencer· 2 shared L. Montorsi· 2 shared T. Le· 2 shared

Activity by Year

2018-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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5 shared papersMicrobiology

A. Suhrbier

Mutual co-authors in cluster

Author profile →

12 papers

Recent·Most cited

PTEN Regulates Myofibroblast Activation in Valvular Interstitial Cells based on Subcellular Localization

D. Batan, G. Tseropoulos, C. Bishop, B. E. Kirkpatrick, K. Bera, A. Khang, M. C. Weiser-Evans, K. S. Anseth

This study shows PTEN suppresses myofibroblast activation in valvular interstitial cells by promoting quiescence and reducing stiffness-induced activation.

bioRxiv · Jun 30, 2024Cell Biology

Harnessing defective interfering particles and lipid nanoparticles for effective delivery of an anti-dengue virus RNA therapy

M.-H. Lin, P. Maniam, D. Li, B. Tang, C. Bishop, A. Suhrbier, L. Wales-Earl, Y. Tayyar, N. A. J. McMillan, L. Li, D. Harrich

This paper demonstrates that DI290-loaded lipid nanoparticles (LNP-290) effectively suppress DENV infection in cell cultures and mice, inducing IFN responses and preventing clinical signs.

bioRxiv · Apr 23, 2024Microbiology

Unanticipated interacting features of human gut-associated lymphoid tissues link microbiota, intestinal immunity and autoimmunity

L. Montorsi, M. J. Pitcher, Y. Zhao, A. Demonti, T. J. Tull, C. Dionisi, P. Dhami, R. J. Ellis, C. Bishop, J. Sanderson, S. Jain, D. D'Cruz, D. Gibbons, T. H. Winkler, M. Bemark, , J. Spencer

The paper identifies DN2 B cells in human GALT that interact with DC expressing DNASE1L3 and C1Q, linking microbiota, immunity, and autoimmunity.

bioRxiv · Aug 29, 2023Immunology

Trem2 Promotes Foamy Macrophage Lipid Uptake and Survival in Atherosclerosis

M. T. Patterson, M. M. Firulyova, Y. Xu, C. Bishop, A. Zhu, P. R. Schrank, C. E. Ronayne, G. Fredrickson, A. E. Kennedy, N. Acharya, X. Revelo, I. M. Stromnes, T. D. Bold, K. Zaitsev, J. W. Williams

This study identifies Trem2 as a regulator of foamy macrophage differentiation and atherosclerotic plaque growth, showing its role in lipid uptake and cell survival.

bioRxiv · Nov 28, 2022Immunology

Disrupted Peyer's patch microanatomy in COVID-19 including germinal centre atrophy independent of local virus

S. C. Trevelin, S. Pickering, K. Todd, C. Bishop, M. Pitcher, J. G. Mesa, L. Montorsi, F. Spada, N. Petrov, A. Green, M. Shankar-Hari, S. J. D. Neil, J. Spencer

This study examines the impact of COVID-19 on ileal Peyer's patches, finding disrupted microanatomy and germinal centre atrophy independent of local viral load.

bioRxiv · Dec 17, 2021Immunology

ACE2-independent SARS-CoV-2 infection and mouse adaption emerge after passage in cells expressing human and mouse ACE2

K. Yan, T. Dumenil, B. Tang, T. T. Le, C. Bishop, A. Suhrbier, D. J. Rawle

The paper describes the generation of mouse-adapted SARS-CoV-2 variants through serial passaging in co-cultures of human and mouse ACE2-expressing cells, revealing ACE2-independent infection capabilities.

bioRxiv · Dec 16, 2021 · PreprintMicrobiology

An inconvenient association between granzyme A and Nicotinamide Nucleotide Transhydrogenase

D. J. Rawle, T. Le, T. Dumenil, C. Bishop, K. Yan, E. Nakayama, P. I. Bird, A. Suhrbier

The paper identifies an association between granzyme A and Nicotinamide Nucleotide Transhydrogenase in mice, showing that Nnt, not GzmA loss, affects disease outcomes and highlights inconsistencies in Nnt sequencing data.

bioRxiv · Mar 16, 2021Immunology

ACE2-lentiviral transduction enables mouse SARS-CoV-2 infection and mapping of receptor interactions

D. J. Rawle, T. T. Le, T. Dumenil, K. Yan, B. Tang, C. Bishop, A. Suhrbier

This paper develops an ACE2-lentivirus system to enable SARS-CoV-2 infection in mice, showing it can model viral replication, inflammation, and vaccine testing.

bioRxiv · Feb 9, 2021Microbiology

Bromodomain and Extraterminal Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV-2 Infection (Pre-Clinical)

R. J. Mills, S. J. Humphrey, P. R. Fortuna, M. Lor, S. R. Foster, G. A. Quaife-Ryan, R. L. Johnston, T. Dumenil, C. Bishop, R. Ruraraju, D. J. Rawle, T. Le, W. Zhao, L. Lee, C. Mackenzie-Kludas, , E

The paper identifies BET inhibitors as potential cardio-protective drugs that block inflammation-induced cardiac dysfunction and SARS-CoV-2 infection in pre-clinical models.

bioRxiv · Aug 23, 2020 · PreprintCell Biology

Arc1 and the microbiota together modulate growth and metabolic traits in Drosophila

S. A. Keith, C. Bishop, S. Fallacaro, B. M. McCartney

The paper shows Arc1 in Drosophila interacts with Acetobacter bacteria to regulate growth and metabolism, with microbiota-dependent expression and phenotypic effects.

bioRxiv · Jul 21, 2020 · PreprintPhysiology

Community turnover by composition and climatic affinity across scales in an alpine system

B. V. Smithers, M. F. Oldfather, M. J. Koontz, J. Bishop, C. Bishop, J. Nachlinger, S. N. Sheth

The paper examines community turnover in alpine plants across elevation gradients at multiple scales, finding strong environmental sorting at broad scales and microclimatic influences at finer scales.

bioRxiv · Aug 8, 2019Ecology

Density dependent enhancement effect of Wolbachia and the host RNAi response to a densovirus in Aedes cells

R. Parry, C. Bishop, L. De Hayr, S. Asgari

The paper shows Wolbachia enhances AalDNV-1 replication in Aedes cells in a density-dependent manner and reports the generation of vpiRNAs in response to DNA virus infection.

bioRxiv · Oct 13, 2018Microbiology