VE607 Stabilizes SARS-CoV-2 Spike In the "RBD-up" Conformation and Inhibits Viral Entry
S. Ding, S. Y. Gong, J. Grover, M. Mohammadjavad, Y. Chen, D. Vezina, G. Beaudoin-Bussieres, V. T. Verma, G. Goyette, J. Richard, D. Yang, A. B. Smith, M. Pazgier, M. Cote, C. Abrams, , C. Baron
VE607 inhibits SARS-CoV-2 infection by stabilizing the RBD in the 'up' conformation and blocking S-ACE2 interaction across multiple variants.
bioRxiv · Feb 3, 2022Microbiology