Evolutionary BiologybioRxiv
CaMKII oxidation is a performance/disease trade-off in vertebrate evolution
Q. Wang, E. O. Hernandez-Ochoa, M. C. Viswanathan…·M. E. Anderson
This study shows CaMKII oxidation by ROS evolved in vertebrates to enhance performance but increased disease risk.
DOI 10.1038/s41467-021-23549-3