M. Nakajima

Extensive distribution of β-1,2-glucanases: finding of new glycoside hydrolase families of β-1,2-glucanases

The paper identifies three new glycoside hydrolase families of β-1,2-glucanases and reveals their functional and structural relationships within a superfamily.

Phytopathogenic cyclic glucohexadecaose from an inverting transglycosylase

This study identifies OpgD as the enzyme responsible for synthesizing CβG16, a key virulence factor in Xanthomonas, revealing a novel transglycosylation mechanism with implications for developing new agrichemicals.

Functional and structural analysis of a cyclization domain in a cyclic beta-1,2-glucan synthase

The paper functionally and structurally analyzes the cyclization domain of a cyclic β-1,2-glucan synthase, revealing it produces cyclic β-1,2-glucans through transglycosylation without hydrolysis and proposes it belongs to a new glycoside hydrolase family.

Microscopic and metatranscriptomic analyses revealed unique cross-domain symbiosis between Candidatus Patescibacteria/candidate phyla radiation (CPR) and methanogenic archaea in anaerobic ecosystems

The paper investigates the interaction between Candidatus Patescibacteria and methanogenic archaea using microscopy and metatranscriptomic analyses, concluding a parasitic relationship.

Biosynthesis of gibberellin-related compounds modulates far-red light responses in the liverwort Marchantia polymorpha

This study shows that GA-related compounds in liverworts modulate far-red light responses, revealing evolutionary conservation and functional divergence in GA biosynthesis.

Novel glycoside hydrolase family enzymes from Escherichia coli are associated with osmo-regulated periplasmic glucan synthesis

The paper identifies OpgG and OpgD from E. coli as β-1,2-glucanases with distinct activities, revealing a new glycoside hydrolase family and a unique reaction mechanism for OpgD.

ncBAF, a chromatin remodeler, enhances PXR-mediated transcriptional activation in the human and mouse liver

This study shows that inhibiting BRD9, a component of ncBAF, reduces PXR-mediated transcriptional activation and associated adverse effects in liver cells and mice.

Satelight: Self-Attention-Based Model for Epileptic Spike Detection from Multi-Electrode EEG

Satelight detects epileptic spikes in EEG using self-attention, achieving high accuracy with fewer parameters than existing models.

Comparative analyses of gene expression in common marmoset and human pluripotent stem cells (PSCs) identify factors enhancing homologous recombination efficiency in the HPRT locus of human PSCs

Basis for the phototaxis sign reversal in the green alga Chlamydomonas reinhardtii studied by high-speed observation

This study identifies two factors determining phototactic sign reversal in Chlamydomonas reinhardtii through high-speed observation and a mathematical model.

Inverse correlation between heme synthesis and the Warburg effect in cancer cells

This study shows that promoting heme synthesis in cancer cells reduces the Warburg effect by shifting energy metabolism from glycolysis to oxidative phosphorylation.