M. Nishio

The differential effect of optogenetic serotonergic manipulation on sustained motor actions and stationary waiting for future rewards in mice

This study investigates how optogenetic manipulation of DRN serotonergic neurons affects motor actions and waiting behavior in mice during reward tasks, finding distinct effects on sustained actions versus stationary waiting.

Microevolution toward loss of photosynthesis: Mutations promoting dark-heterotrophic growth and suppressing photosynthetic growth in cyanobacteria

The paper reports mutations in cyanobacteria that lead to loss of photosynthetic growth and promote dark-heterotrophic growth through a single gene mutation.

Medial prefrontal cortex suppresses reward-seeking behavior with risk of positive punishment by reducing sensitivity to reward

This study shows that medial prefrontal cortex (mPFC) reduces reward-seeking behavior under positive punishment risk by decreasing reward sensitivity, but not negative punishment.

Human iPSC-derived hypertrophic chondrocytes reveal a mutation-specific unfolded protein response in chondrodysplasias

The paper evaluates mutation-specific unfolded protein response in chondrodysplasias using human iPSC-derived hypertrophic chondrocytes and identifies differential ER stress and gene expression changes.