Author

M. O. Roth

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. Das· 1 shared H. Li· 1 shared J. Rai· 1 shared M. L. Medina· 1 shared M. R. Barakat· 1 shared Y. Shu· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

A. Das

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintSep 10, 2022

Conformational Changes Regulate Metal Coordination in the Catalytic Sites of Cas9

A. Das, J. Rai, M. O. Roth…·H. Li

This study presents cryo-EM structures of AceCas9 at different states to show how conformational changes regulate metal coordination and catalytic activity.

DOI 10.1101/2022.09.10.507422

cryo-EMexperimental assay

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