Molecular evolution of classic Hodgkin lymphoma revealed through whole genome sequencing of Hodgkin and Reed Sternberg cells
F. MAURA, B. Ziccheddu, J. J. Xiang, B. Bhinder, F. Abascal, K. Maclachlan, K. W. Eng, M. Uppal, F. He, W. Zhang, Q. Gao, V. Yellapantula, S. Park, M. Oberley, E. Ruckdeschel, , L. Giulino-Roth
This study uses whole genome sequencing of Hodgkin and Reed Sternberg cells to reconstruct the temporal evolution of classic Hodgkin lymphoma, identifying key mutations and structural variants.
bioRxiv · Nov 5, 2021Cancer Biology