Author

K. Maclachlan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

F. MAURA· 2 shared O. Landgren· 2 shared V. Yellapantula· 2 shared Y. Zhang· 2 shared A. Dogan· 1 shared A. M. Lesokhin· 1 shared A. Makohon-Moore· 1 shared B. Bhinder· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

F. MAURA

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Author profile →

2 papers

Recent·Most cited

Molecular evolution of classic Hodgkin lymphoma revealed through whole genome sequencing of Hodgkin and Reed Sternberg cells

F. MAURA, B. Ziccheddu, J. J. Xiang, B. Bhinder, F. Abascal, K. Maclachlan, K. W. Eng, M. Uppal, F. He, W. Zhang, Q. Gao, V. Yellapantula, S. Park, M. Oberley, E. Ruckdeschel, , L. Giulino-Roth

This study uses whole genome sequencing of Hodgkin and Reed Sternberg cells to reconstruct the temporal evolution of classic Hodgkin lymphoma, identifying key mutations and structural variants.

bioRxiv · Nov 5, 2021Cancer Biology

Accelerated single cell seeding in relapsed multiple myeloma

H. J. Landau, V. Yellapantula, B. J. Diamond, E. H. Rustad, K. Maclachlan, G. Gundem, J. Medina-Martinez, J. E. Arango Ossa, M. Levine, Y. Zhou, K. L. Rajya, P. Baez, M. Attiyeh, A. Makohon-Moore, L. Zhang, , F. Maura

This study uses whole genome sequencing to show that relapsed multiple myeloma exhibits accelerated systemic seeding driven by chemotherapy-induced mutations and clonal expansion of single myeloma cells.

bioRxiv · Feb 25, 2020Cancer Biology