Author

M. P. Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1

Frequent Co-Authors

C. Francavilla· 3 shared J. Watson· 3 shared P. Fullwood· 3 shared A. F. L. Hurlstone· 2 shared D. J. Wilcock· 2 shared D. Knight· 2 shared H. R. Ferguson· 2 shared J. Ferguson· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

C. Francavilla

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

PARP14 inhibition restores PD-1 immune checkpoint inhibitor response following IFNγ-driven adaptive resistance

C. W. Wong, C. Evangelou, K. N. Sefton, R. Leshem, K. Sergiou, M. L. Fernandez Carro, E. Uzuner, H. Mole, B. A. Telfer, D. J. Wilcock, M. P. Smith, K. Kunii, N. R. Perl, P. Lorigan, K. J. Williams, , A. F. L. Hurlstone

This study shows that PARP14 inhibition restores PD-1 checkpoint inhibitor response in IFNγ-resistant tumors by increasing T cell infiltration and reducing regulatory T cells.

Nature Communications · Sep 26, 2023Peer-reviewedCancer Biology

Spatially Resolved Phosphoproteomics Reveals Fibroblast Growth Factor Receptor Recycling-driven Regulation of Autophagy and Survival

J. Watson, H. R. Ferguson, R. M. Brady, J. Ferguson, P. Fullwood, H. Mo, K. H. Bexley, D. Knight, J.-M. Schwartz, M. P. Smith, C. Francavilla

The paper uses spatially resolved phosphoproteomics to show FGFR2b recycling activates mTOR and ULK1, suppressing autophagy and promoting cell survival in cancer cells.

bioRxiv · Dec 4, 2021Cell Biology

Reciprocal Priming between RTKs at Recycling Endosomes Orchestrates Cellular Signaling Outputs

M. P. Smith, H. R. Ferguson, J. Ferguson, E. Zindy, K. M. Kowalczyk, T. Kedward, C. Bates, J. Parsons, J. Watson, S. Chandler, P. Fullwood, S. Warwood, D. Knight, R. B. Clarke, C. Francavilla

The paper identifies reciprocal priming between FGFRs and EGFR at recycling endosomes that coordinates signaling outputs in breast cancer cells.

bioRxiv · Jan 4, 2021Cell Biology

DGAT1 is a lipid metabolism oncoprotein that enables cancer cells to accumulate fatty acid while avoiding lipotoxicity

D. J. Wilcock, A. P. Badrock, R. Owen, M. Guerin, A. D. Southam, H. Johnston, S. Ogden, P. Fullwood, J. Watson, H. Ferguson, J. Haworth, D. A. Richardson, G. R. Lloyd, A. Jankevics, W. B. Dunn, , A. F. L. Hurlstone

This study identifies DGAT1 as an oncoprotein that enables cancer cells to accumulate fatty acids while avoiding lipotoxicity, promoting melanoma formation.

bioRxiv · Jun 23, 2020 · PreprintCancer Biology