M. P. Wear

This study uses NMR and MD simulations to determine the structure of a synthetic C. neoformans polysaccharide, revealing its extended conformation and structural features recognized by protective antibodies.

This study shows that lyophilization alters the structure of Cryptococcus neoformans exopolysaccharide, reducing antibody binding.

This study isolates and characterizes Cryptococcus neoformans capsule polysaccharides using physical and enzymatic methods, revealing that the capsule is assembled from smaller polymers added distally.

This paper investigates how the constant region, specifically the hinge, influences antigen binding in murine IgG antibodies targeting Cryptococcus neoformans capsule polysaccharides, showing that the hinge is necessary but not sufficient for binding differences between isotypes.

This study uses a hydroxylamine-armed fluorescent probe to investigate the structure and assembly of the Cryptococcus neoformans capsule, revealing reducing ends at the cell wall surface.