Identification of tumor-intrinsic drivers of immune exclusion in acral melanoma
R. C. Augustin, S. Newman, A. Li, M. Joy, M. Lyons, M. Pham, P. C. Lucas, K. Smith, C. Sander, B. Isett, D. Davar, Y. G. Najjar, H. M. Zarour, J. M. Kirkwood, J. J. Luke, R. Bao
This study identifies 11 oncogenic pathways associated with immune exclusion and ICI resistance in acral melanoma, suggesting therapeutic targets for immunotherapy combinations.
bioRxiv · Aug 24, 2023Cell Biology