M. R. Barron

This study shows that intestinal inflammation in a mouse model alters microbiota composition, increasing susceptibility to C. difficile colonization, and that reducing inflammation restores colonization resistance.

This study shows pre-colonization with a less virulent C. difficile strain reduces germination of a lethal strain by limiting glycine availability, offering a mechanism for protective intraspecies competition.

This study shows that intestinal inflammation and altered gut microbiota in IBD make mice susceptible to C. difficile colonization and infection, highlighting the role of IBD-induced microbiota in disease severity.

This study shows that E. coli lacking RpoS has reduced colonization ability in human intestinal organoids but not in germ-free mice, indicating different stress environments in these models.