Machine learning classification by fitting amplicon sequences to existing OTUs
C. R. Armour, K. L. Sovacool, W. L. Close, B. D. Topcuoglu, J. Wiens, P. D. Schloss
The paper evaluates OptiFit, a method to fit new sequences to existing OTUs, finding it performs as well or better than de novo and database-reference-based clustering in classifying colonic screen relevant neoplasia.
bioRxiv · Sep 1, 2022Microbiology