BiophysicsbioRxiv
The homeodomain drives favorable DNA binding energetics of prostate cancer target ONECUT2
A. Chatterjee, B. Gallent, M. Katiki…·R. Murali
This study shows the homeodomain stabilizes ONECUT2-DNA binding through allosteric modulation and conserved base interactions, with implications for prostate cancer.
DOI 10.1038/s41467-024-53159-8