Author

M. R. Hayden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Hill· 1 shared A. J. Cutts· 1 shared B. R. Leavitt· 1 shared C. J. Cohen· 1 shared C. Young· 1 shared D. Castano Mayan· 1 shared D.-G. Jo· 1 shared E. A. Liehn· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCancer Biology

A. Hill

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Author profile →

3 papers

Recent·Most cited

Pharmacology & ToxicologyThe Journal of Pharmacology and Experimental TherapeuticsPeer-reviewedJul 1, 2023

Potent, Gut-Restricted Inhibitors of Divalent Metal Transporter 1 (DMT1): Preclinical Efficacy Against Iron Overload and Safety Evaluation

A. J. Cutts, S. Chowdhury, L. Ratkay…·C. J. Cohen

This paper identifies XEN602, a potent, gut-restricted DMT1 inhibitor, showing efficacy in reducing iron overload in rats and pigs with minimal systemic exposure.

DOI 10.1124/jpet.122.001435

ratplant (other)

𝕏 PostBluesky

PhysiologybioRxivPreprintDec 11, 2022

Absence of the bile acid enzyme CYP8B1 increases brain chenodeoxycholic acid and reduces neuronal excitotoxicity in mice

V. F. Monteiro-Cardoso, X. Y. Yeo, H.-G. Bae…·R. R. Singaraja

This study shows that absence of CYP8B1 increases brain chenodeoxycholic acid (CDCA) levels, reducing neuronal excitotoxicity and stroke infarct area in mice.

DOI 10.1101/2022.12.11.520005

mouseproteomics

𝕏 PostBluesky

Cancer BiologybioRxivPreprintSep 11, 2022

Huntingtin Over-Expression Does Not Alter Overall Survival in Murine Cancer Models

L. Chan, A. Hill, G. Lu…·B. R. Leavitt

This study tests if mutant huntingtin protects against cancer by over-expressing it in murine cancer models, finding no effect on survival.

DOI 10.1101/2022.09.11.507440

mouseexperimental assay

𝕏 PostBluesky