Author

M. Ragavan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:metabolomics· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

M. Merritt· 2 shared A. D. Rao· 1 shared A. Giacalone· 1 shared A. Kaushik· 1 shared A. Rushin· 1 shared A. Tarangelo· 1 shared B. Faubert· 1 shared B. S. P. Slusher· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

M. Merritt

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Author profile →

3 papers

Recent·Most cited

Detecting altered hepatic lipid oxidation by MRI in an animal model of NAFLD

M. A. McLeod, M. Ragavan, M. Chang, R. Mahar, A. Giacalone, A. Rushin, M. Glanz, V. Malut, D. Graham, N. Sunny, M. Merritt

This study develops an MRI-based method to detect altered hepatic lipid oxidation in a NAFLD mouse model, showing decreased β-oxidation efficiency as a potential prognostic indicator.

bioRxiv · Aug 16, 2023 · PreprintBiochemistry

In-vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma

A. Kaushik, L. K. Burroughs, A. Tarangelo, M. Ragavan, C.-Y. Wu, X. Li, K. Ahumada, V. T. Tcheuyap, F. Saatchi, Q. Do, C. Yong, T. Rosales, C. Stevens, A. D. Rao, B. Faubert, , R. J. DeBerardinis

The paper identifies multiple glutamine metabolism pathways in ccRCC tumorgrafts and shows that targeting amidotransferase activity reduces tumor growth.

bioRxiv · Oct 31, 2022Cancer Biology

Hepatic Mitochondrial Remodeling is Mechanistically Linked to Insulin Resistance in Nonalcoholic Fatty Liver Disease

C. E. Shannon, M. Ragavan, J. P. Palavicini, M. Fourcaudot, T. Bakewell, E. S. Jin, C. R. Malloy, X. Han, M. E. Merritt, L. Norton

This study links insulin resistance and mitochondrial remodeling in NAFLD, showing that insulin sensitization improves mitochondrial function without reducing lipid content.

bioRxiv · Jan 2, 2020Biochemistry