M. Ramirez

Inter-species gene flow drives ongoing evolution of Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis

The paper shows extensive genomic overlap between Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis, including shared genes and recombination events, with implications for vaccine development.

Analysis of small EV proteomes reveals unique functional protein networks regulated by VAP-A

The paper identifies proteins regulated by VAP-A in EVs and shows their involvement in RNA machinery sorting.

Beyond the MEP Pathway: a novel kinase required for prenol utilization by malaria parasites

This study identifies a novel kinase in malaria parasites that enables prenol salvage, showing its role in bypassing MEP pathway inhibition and enhancing drug efficacy.

Targeting H3K4 methylation as a novel therapeutic strategy against tumor infiltration and nuclear changes of acute lymphoblastic leukemia cells.

This study shows that targeting H3K4 methylation via WDR5 inhibition reduces leukemia cell invasion in vitro and tissue infiltration in vivo, revealing a novel therapeutic strategy for acute lymphoblastic leukemia.

Novel repellents for the blood-sucking insects Rhodnius prolixus and Triatoma infestans, vectors of Chagas disease

This study identifies volatile compounds from human skin microbiota that repel two Chagas disease vectors, with some compounds being more effective than DEET at lower doses.

Transgenic mice expressing tunable levels of DUX4 develop characteristic facioscapulohumeral muscular dystrophy-like pathophysiology ranging in severity

This paper develops a bi-transgenic mouse model that allows controlled expression of DUX4 to study FSHD-like pathophysiology with varying severity.