Author

M. Sabat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Organism:zebrafish· 1

Frequent Co-Authors

R. Myers· 2 shared A. Barilli· 1 shared C. Fung· 1 shared D. B. Sargent· 1 shared D. N. Kasal· 1 shared E. Haley· 1 shared I. Orozco· 1 shared J. Du· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

R. Myers

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Tuft cell-derived acetylcholine regulates epithelial fluid secretion

T. E. Billipp, C. Fung, L. M. Webeck, D. B. Sargent, M. B. Gologorsky, M. M. McDaniel, D. N. Kasal, J. W. McGinty, K. A. Barrow, L. M. Rich, A. Barilli, M. Sabat, J. S. Debley, R. Myers, M. R. Howitt, J. von Moltke

This study shows that tuft cell-derived acetylcholine in the intestine triggers immediate fluid secretion, distinct from its role in immune responses, and is involved in Type 2 inflammation and helminth clearance.

bioRxiv · Mar 17, 2023 · PreprintImmunology

Structures of TRPM5 channel elucidate mechanism of activation and inhibition

W. Lu, J. Du, Z. Ruan, E. Haley, I. Orozco, R. Roth, M. Sabat, R. Myers

This paper reports cryo-EM structures of TRPM5 channels in different states, revealing mechanisms of activation and inhibition through ligand binding sites.

bioRxiv · Mar 25, 2021Biophysics