Tumor removal limits prostate cancer cell dissemination in bone and osteoblasts induce cancer cell dormancy through focal adhesion kinase
R. Liu, S. Su, J. Xing, K. Liu, Y. Zhao, M. Stangis, D. P. Jacho, E. D. Yildirim-Ayan, C. M. Gatto-Weis, B. Chen, X. Li
This study shows that tumor removal increases prostate cancer cell dissemination to bones, while osteoblasts induce dormancy through focal adhesion kinase inhibition.
bioRxiv · Sep 2, 2022Cancer Biology