Evolutionary BiologybioRxivPreprint
Vector and cell-culture passaging of dengue clinical samples for virus isolation and amplification does not significantly change genome consensus or frequencies of intra-host viral variants
C. Fung, T. Li, S. Pollett…·I. Maljkovic Berry
This study shows that low-passage dengue virus isolates preserve the consensus sequence and intra-host variant frequencies of their clinical samples, making them suitable for genomic epidemiology.
DOI 10.1101/2020.08.17.254417