MicrobiologybioRxivPreprint
Norovirus replication in human intestinal epithelial cells is restricted by the interferon-induced JAK/STAT signalling pathway and RNA Polymerase II mediated transcriptional responses.
M. T. Hosmillo, Y. Chaudhry, K. Nayak…·I. G. Goodfellow
This study shows that HuNoV replication in intestinal epithelial cells is restricted by IFN-induced transcriptional responses and that inhibiting these responses enhances viral replication.
DOI 10.1101/731802