Author

M. Trakala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

M. Malumbres· 3 shared M. Alvarez-Fernandez· 2 shared M. Salazar-Roa· 2 shared O. Grana Castro· 2 shared A. Gomez-Caturla· 1 shared A. Hernandez-Nunez· 1 shared A. Osorio· 1 shared A. Sanchez-Belmonte· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCell Biology

M. Malumbres

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Bilallelic germline mutations in MAD1L1 induce a novel syndrome of aneuploidy with high tumor susceptibility

C. Villarroya-Beltri, A. Osorio, R. Torres-Ruiz, D. Gomez-Sanchez, M. Trakala, A. Sanchez-Belmonte, F. Mercadillo, B. Pitarch, A. Hernandez-Nunez, A. Gomez-Caturla, D. Rueda, J. Perea, S. Rodriguez-Perales, M. Malumbres, M. Urioste

This study identifies biallelic MAD1L1 mutations causing aneuploidy and high tumor susceptibility, with systemic inflammation and clonal expansions observed in patient blood cells.

bioRxiv · Aug 8, 2022 · PreprintCancer Biology

Proliferative advantage of specific aneuploid cells drives evolution of tumor karyotypes

I. Ban, L. Tomasic, M. Trakala, I. M. Tolic, N. Pavin

This paper introduces a mathematical model to explain how proliferative advantage of specific aneuploid cells drives tumor karyotype evolution through chromosome gains and losses.

bioRxiv · Apr 14, 2022Biophysics

miR-203 imposes an intrinsic barrier during cellular reprogramming by targeting NFATC2

M. Salazar-Roa, S. Martinez-Martinez, O. Grana Castro, M. Alvarez-Fernandez, M. Trakala, J. M. Redondo, M. Malumbres

This study identifies miR-203 as an intrinsic barrier to cellular reprogramming by repressing NFATC2, showing that its removal enhances reprogramming efficiency.

bioRxiv · Jun 2, 2020 · PreprintCell Biology

A novel microRNA-based strategy to expand the differentiation potency of stem cells

M. Salazar-Roa, M. Trakala, M. Alvarez-Fernandez, F. Valdes-Mora, C. Zhong, J. Munoz, Y. Yu, T. J. Peters, O. Grana Castro, R. Serrano, E. Zapatero-Solana, M. Abad, M. J. Bueno, M. Gomez de Cedron, J. Fernandez-Piqueras, , M. Malumbres

This study shows that transient exposure to miR-203 enhances the differentiation capacity of murine and human PSCs by reversing DNA methylation.

bioRxiv · Nov 4, 2019Cell Biology