Author

M. W. Pastok

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

J. A. Endicott· 2 shared A. Basle· 1 shared B. C. Montefiore· 1 shared D. J. Wood· 1 shared F. Sobott· 1 shared G. Zenkeviciute· 1 shared J. R. Ault· 1 shared J. Reeks· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

J. A. Endicott

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2 papers

Recent·Most cited

BiochemistrybioRxivJul 1, 2021

Nanobodies restore stability to cancer-associated mutants of tumor suppressor protein p16INK4a

O. Burbidge, M. W. Pastok, S. L. Hodder…·L. Itzhaki

This paper shows nanobodies stabilize p16INK4a mutants and restore their function by binding to a site distinct from CDK6, enabling ternary complex formation.

DOI 10.1016/j.str.2025.07.017

humanprotein structure

𝕏 PostBluesky

BiochemistrybioRxivOct 8, 2020

Discriminative SKP2 interactions with CDK-cyclin complexes support a cyclin A-specific role in p27KIP1 degradation

M. Salamina, B. C. Montefiore, M. Liu…·J. A. Endicott

The paper identifies a cyclin A-specific interaction between SKP2 and CDK2-cyclin A complexes that promotes p27KIP1 degradation, distinguishing cyclin A from other G1 cyclins.

DOI 10.1016/j.jmb.2020.166795

experimental assaycell signaling & trafficking

𝕏 PostBluesky