Author

M. Yigit

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

D. Unutmaz· 2 shared L. Kozhaya· 2 shared L. Placek· 2 shared M. Dogan· 2 shared A. Sendoel· 1 shared C. Dure· 1 shared D. Spies· 1 shared D. Taborsky· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

D. Unutmaz

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Engineering human Mucosal Associated Invariant T (MAIT) cells with chimeric antigen receptors for cancer immunotherapy

M. Dogan, E. Karhan, L. Kozhaya, L. Placek, X. Chen, M. Yigit, D. Unutmaz

This paper engineers MAIT cells with CARs to target cancer cells, showing comparable cytotoxicity to CD8+ CAR-T cells but with lower IFN-γ expression.

bioRxiv · Jul 28, 2022 · PreprintImmunology

Targeting SARS-CoV-2 infection through CAR-T like bispecific T cell engagers incorporating ACE2

M. Dogan, L. Kozhaya, L. Placek, F. Karabacak, M. Yigit, D. Unutmaz

This paper develops a bispecific T cell engager (ACE2-Bite) that targets SARS-CoV-2 infected cells and neutralizes variants, showing higher affinity for Delta and Omicron.

bioRxiv · Jan 19, 2022Bioengineering

Monitoring the 5`UTR landscape reveals 5`terminal oligopyrimidine (TOP) motif switches to drive translational efficiencies

R. Weber, U. Ghoshdastider, D. Spies, C. Dure, F. Valdivia-Francia, M. Forny, M. Ormiston, P. F. Renz, D. Taborsky, M. Yigit, H. Yamahachi, A. Sendoel

The paper uses long-read sequencing to analyze 5'UTR isoforms in epidermal stem cells and squamous cell carcinomas, showing TOP motif switches affect translational efficiency.

bioRxiv · Jul 2, 2021 · PreprintCancer Biology