Author

A. Sendoel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

F. Valdivia-Francia· 2 shared M. Forny· 2 shared M. Ormiston· 2 shared P. F. Renz· 2 shared R. Weber· 2 shared U. Ghoshdastider· 2 shared A. E. Moor· 1 shared A. Gola· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

F. Valdivia-Francia

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

In vivo single-cell CRISPR uncovers distinct TNF-alphaprograms in clonal expansion and tumorigenesis

P. F. Renz, U. Ghoshdastider, S. Baghai Sain, F. Valdivia-Francia, A. Khandekar, M. Ormiston, M. Bernasconi, J. A. Kretz, M. Lee, K. Hyams, M. Forny, M. Pohly, X. Ficht, S. J. Ellis, A. E. Moor, A. Sendoel

This study uses in vivo single-cell CRISPR to identify distinct TNF-α programs in clonal expansion and tumorigenesis, showing their roles in epithelial transformation and tumor initiation.

bioRxiv · Jul 13, 2023 · PreprintCancer Biology

In vivo CRISPR screens reveal SCAF1 and USP15 as novel drivers of pancreatic cancer

S. Martinez, R. Weber, T. Woo, A. Malik, M. Geuenich, G. H. Jang, D. Dervovic, K. Al-Zahrani, R. Tsai, N. Fodil, P. Gros, S. S. Sidhu, S. Gallinger, G. Neely, K. Campbell, , D. Schramek

This study uses in vivo CRISPR screens to identify USP15 and SCAF1 as novel tumor suppressors in pancreatic cancer, with potential therapeutic implications.

bioRxiv · Mar 13, 2022Cancer Biology

The integrated stress response remodels the microtubule organizing center to clear unfolded proteins following proteotoxic stress

E. Fuchs, B. Hurwitz, N. Guzzi, A. Gola, V. F. Fiore, A. Sendoel, M. Nikolova, D. Barrows, T. S. Carroll, H. A. Pasolli

This study shows that the integrated stress response (ISR) redirects translation to centrosomal proteins to clear unfolded proteins at the microtubule organizing center during proteotoxic stress in SCC stem cells.

bioRxiv · Feb 13, 2022Cell Biology

Monitoring the 5`UTR landscape reveals 5`terminal oligopyrimidine (TOP) motif switches to drive translational efficiencies

R. Weber, U. Ghoshdastider, D. Spies, C. Dure, F. Valdivia-Francia, M. Forny, M. Ormiston, P. F. Renz, D. Taborsky, M. Yigit, H. Yamahachi, A. Sendoel

The paper uses long-read sequencing to analyze 5'UTR isoforms in epidermal stem cells and squamous cell carcinomas, showing TOP motif switches affect translational efficiency.

bioRxiv · Jul 2, 2021 · PreprintCancer Biology