Author

M. Zagorulya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

S. Spranger· 2 shared A. Ali· 1 shared A. Luengo· 1 shared A. Naamati· 1 shared B. L. Horton· 1 shared B. T. Do· 1 shared C. A. Lewis· 1 shared C. J. Thomas· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersImmunology

S. Spranger

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2 papers

Recent·Most cited

Differentiation and Expansion of Tumor-Infiltrating T Cell Clonotypes Occurs in the Spleen Following Immune Checkpoint Blockade

D. M. Morgan, B. L. Horton, M. Zagorulya, J. C. Love, S. Spranger

This study identifies spleen-resident intermediate-exhausted T cells as key to ICB efficacy, showing their expansion and differentiation into tumor-infiltrating clonotypes.

bioRxiv · Sep 4, 2023 · PreprintImmunology

Increased demand for NAD+ relative to ATP drives aerobic glycolysis

A. Luengo, Z. Li, D. Y. Gui, L. B. Sullivan, M. Zagorulya, B. T. Do, R. Ferriera, A. Naamati, A. Ali, C. A. Lewis, C. J. Thomas, S. Spranger, N. J. Matheson, M. G. Vander Heiden

The paper shows that increased NAD+ demand relative to ATP demand drives aerobic glycolysis by impairing NAD+ regeneration and promoting fermentation.

bioRxiv · Jun 8, 2020Biochemistry