Author

A. Naamati

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:proteomics· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

N. J. Matheson· 5 shared E. J. Greenwood· 4 shared J. C. Williamson· 3 shared P. J. Lehner· 3 shared S. Marelli· 3 shared A. V. Protasio· 2 shared A. Ali· 1 shared A. E. Willis· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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5 shared papersMicrobiology

N. J. Matheson

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Author profile →

5 papers

Recent·Most cited

A protease-activatable luminescent biosensor andreporter cell line for authentic SARS-CoV-2 infection

P. Pereyra Gerber, L. M. Duncan, E. J. Greenwood, S. Marelli, A. Naamati, A. Teixeira-Silva, T. W. Crozier, I. Gabaev, J. R. Zhan, T. E. Mulroney, E. C. Horner, R. Doffinger, A. E. Willis, J. E. Thanventhiran, A. V. Protasio, N. J. Matheson

This paper develops a luminescent biosensor and reporter cell line to quantify SARS-CoV-2 infection and neutralising antibodies efficiently.

bioRxiv · Mar 22, 2021Microbiology

Increased demand for NAD+ relative to ATP drives aerobic glycolysis

A. Luengo, Z. Li, D. Y. Gui, L. B. Sullivan, M. Zagorulya, B. T. Do, R. Ferriera, A. Naamati, A. Ali, C. A. Lewis, C. J. Thomas, S. Spranger, N. J. Matheson, M. G. Vander Heiden

The paper shows that increased NAD+ demand relative to ATP demand drives aerobic glycolysis by impairing NAD+ regeneration and promoting fermentation.

bioRxiv · Jun 8, 2020Biochemistry

Antagonism of PP2A is an independent and conserved function of HIV-1 Vif and causes cell cycle arrest

S. Marelli, J. C. Williamson, A. V. Protasio, A. Naamati, E. J. Greenwood, J. E. Deane, P. J. Lehner, N. J. Matheson

This study identifies HIV-1 Vif amino acid polymorphisms that regulate PP2A antagonism and demonstrate that this function causes G2/M cell cycle arrest independently of APOBEC3 proteins.

bioRxiv · Oct 31, 2019Microbiology

Promiscuous targeting of cellular proteins by Vpr drives massive proteomic remodelling in HIV-1 infection

E. J. Greenwood, J. C. Williamson, A. Sienkiewicz, A. Naamati, N. J. Matheson, P. J. Lehner

The paper identifies Vpr as the main driver of proteomic changes in HIV-1 infection by degrading multiple host proteins.

bioRxiv · Jan 8, 2019Microbiology

Functional proteomic atlas of HIV-infection inprimary human CD4+ T cells

A. Naamati, J. C. Williamson, E. J. Greenwood, S. Marelli, P. J. Lehner, N. J. Matheson

This study provides a functional proteomic atlas of HIV infection in primary human CD4+ T cells, revealing 650 significantly perturbed proteins, many regulated by viral accessory proteins.

bioRxiv · Aug 10, 2018Microbiology