Author

M.-S. Liu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2

Frequent Co-Authors

D. W. Taylor· 2 shared K. A. Johnson· 2 shared K. Jung· 2 shared H.-H. Yu· 1 shared J. P. Bravo· 1 shared R. S. McCool· 1 shared S. Gong· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

D. W. Taylor

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2 papers

Recent·Most cited

BiochemistrybioRxivSep 14, 2021

Structural basis for mismatch surveillance by CRISPR/Cas9

J. P. Bravo, M.-S. Liu, R. S. McCool…·D. W. Taylor

This study identifies a linear gRNA:DNA duplex conformation that prevents Cas9 activation in the presence of PAM-distal mismatches, offering insights for improving Cas9 specificity.

DOI 10.1038/s41586-022-04470-1

experimental assayprotein folding & dynamics

𝕏 PostBluesky

BiochemistrybioRxivPreprintMay 8, 2019

Basis for discrimination by engineered CRISPR/Cas9 enzymes

M.-S. Liu, S. Gong, H.-H. Yu…·D. W. Taylor

This study investigates how engineered CRISPR/Cas9 variants improve off-target discrimination by analyzing their kinetic behavior during DNA cleavage.

DOI 10.1101/630509

experimental assayprotein folding & dynamics

𝕏 PostBluesky