N. Bennett

Cryo-electron microscopy of the f1 filamentous phage reveals a new paradigm in viral infection and assembly

The paper determines the structure of a filamentous phage using cryo-electron microscopy and identifies key domains involved in infection and assembly.

Improving de novo Protein Binder Design with Deep Learning

This paper improves de novo protein binder design by using deep learning models to assess design success rates and computational efficiency.

Robust deep learning based protein sequence design using ProteinMPNN

A deep learning method for protein sequence design shows high performance in both simulations and experiments, applicable to various design challenges.

In vivo CRISPRi screen reveals the differential requirement for mitochondrial respiratory chain function between in vivo and in vitro tumor growth

The paper uses CRISPRi to show that mitochondrial respiratory chain genes are critical for in vivo tumor growth but not for metastasis in lung cancer xenografts.

Ivermectin converts cold tumors hot and synergies with immune checkpoint blockade for treatment of breast cancer

This paper shows ivermectin converts cold tumors to hot by inducing immunogenic cancer cell death and enhancing T cell infiltration, synergizing with anti-PD1 to improve breast cancer treatment outcomes.