Myeloid Tribbles 1 induces early atherosclerosis via enhanced foam cell expansion
J. Johnston, A. Angyal, R. Bauer, S. Hamby, K. Suvarna, K. Baidzajevas, Z. Hegedus, N. Dear, M. Turner, The Cardiogenics Consortium, H. Wilson, A. Goodall, D. J. Rader, C. C. Shoulders, S. Francis, E. Kiss-Toth
This study shows that myeloid Trib1 promotes early atherosclerosis by enhancing foam cell formation through increased lipid uptake and OLR1 expression.
bioRxiv · May 5, 2019Immunology