Author

N. Doyle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Organism:chicken / avian· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

H. J. Maier· 2 shared J. Simpson· 2 shared P. C. Hawes· 2 shared A. E. Firth· 1 shared B. G. Hale· 1 shared C. Lefevre· 1 shared E. Bickerton· 1 shared G. Dowgier· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

H. J. Maier

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Coronavirus RNA synthesis takes place within membrane-bound sites

N. Doyle, J. Simpson, P. C. Hawes, H. J. Maier

This study shows that coronavirus RNA synthesis occurs within membrane-bound compartments in host cells, a finding conserved across all four coronavirus genera, including SARS-CoV-2.

bioRxiv · Nov 4, 2021Microbiology

Manipulation of the unfolded protein response: a pharmacological strategy against coronavirus infection

L. Echavarria-Consuegra, G. M. Cook, I. Busnadiego, C. Lefevre, S. Keep, K. Brown, N. Doyle, G. Dowgier, K. Franaszek, N. A. Moore, S. G. Siddell, E. Bickerton, B. G. Hale, A. E. Firth, I. Brierley, N. Irigoyen

This paper investigates the unfolded protein response (UPR) in coronavirus infection and shows that pharmacological inhibition of the UPR significantly reduces viral replication.

bioRxiv · Mar 19, 2021Microbiology

Infectious bronchitis virus regulates cellular stress granule signaling

M. J. Brownsword, N. Doyle, M. Brocard, N. Locker, H. J. Maier

This study investigates how infectious bronchitis virus modulates cellular stress granule signaling and translational repression during infection.

bioRxiv · Oct 28, 2019Microbiology

The porcine deltacoronavirus replication organelle comprises double membrane vesicles and zippered endoplasmic reticulum with double membrane spherules

N. Doyle, P. C. Hawes, J. Simpson, L. H. Adams, H. Maier

bioRxiv · Jul 31, 2019Microbiology