Author

E. Bickerton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

A. E. Firth· 1 shared A. Zagrajek· 1 shared B. G. Hale· 1 shared C. Conceicao· 1 shared C. Lefevre· 1 shared C. Tsirigoti· 1 shared D. Bailey· 1 shared D. Bialy· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. E. Firth

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Author profile →

2 papers

Recent·Most cited

Manipulation of the unfolded protein response: a pharmacological strategy against coronavirus infection

L. Echavarria-Consuegra, G. M. Cook, I. Busnadiego, C. Lefevre, S. Keep, K. Brown, N. Doyle, G. Dowgier, K. Franaszek, N. A. Moore, S. G. Siddell, E. Bickerton, B. G. Hale, A. E. Firth, I. Brierley, N. Irigoyen

This paper investigates the unfolded protein response (UPR) in coronavirus infection and shows that pharmacological inhibition of the UPR significantly reduces viral replication.

bioRxiv · Mar 19, 2021Microbiology

The SARS-CoV-2 Spike protein has a broad tropism for mammalian ACE2 proteins

C. Conceicao, N. Thakur, S. Human, J. T. Kelly, L. Logan, D. Bialy, S. Bhat, P. Stevenson-Leggett, A. Zagrajek, P. Hollinghurst, M. Varga, C. Tsirigoti, J. Hammond, H. J. Maier, E. Bickerton, , D. Bailey

This study shows SARS-CoV-2 Spike protein can bind to ACE2 receptors from multiple mammals, indicating broad host tropism and potential for zoonotic transmission.

bioRxiv · Jun 17, 2020Microbiology