N. G. Barra

This study shows that gut microbiota-based vaccination improves blood glucose control in obese mice by engaging innate immunity, requiring bacterial components and specific immune proteins.

The paper shows that the type of lipopolysaccharide (LPS) determines metabolic endotoxemia effects, with E. coli LPS causing dysglycemia and inflammation while R. sphaeroides LPS has beneficial effects.

This study identifies IRE1 kinase as a mediator of inflammation-induced adipocyte lipolysis, distinct from adrenergic or hormonal regulation.

This study shows that RIPK2 limits the insulin sensitizing effect of gefitinib, while imatinib increases insulin secretion in obese mice, indicating TKI actions on RIPK2 dictate divergent insulin responses.