TMEM120 is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase
J. Xue, Y. Han, H. Baniasadi, W. Zeng, J. Pei, N. Grishin, J. Wang, B. P. Tu, Y. Jiang
The paper presents the cryo-EM structure of TMEM120A, revealing it binds coenzyme A and shares structural features with ELOVL fatty acid elongase, suggesting a potential role in fatty acid metabolism rather than mechanosensation.
bioRxiv · Jun 13, 2021Biophysics