Cancer BiologybioRxivPreprint
Adaptive immunity is required for durable responses to alectinib in murine models of EML4-ALK lung cancer
E. K. Kleczko, T. K. Hinz, T. T. Nguyen…·R. A. Nemenoff
This paper shows that adaptive immunity enhances the durability of alectinib response in EML4-ALK lung cancer models, with CD8+ T cells playing a key role.
DOI 10.1101/2022.04.14.488385