T. T. Nguyen

The paper shows longer bacterial cells gain a competitive advantage during range expansion through collective alignment, blocking shorter cells from resources.

This study shows physical activity reduces breast cancer risk by improving HSC function and enhancing cancer immunosurveillance through reduced oxidative stress and altered T cell differentiation.

This paper develops a chimeric oncolytic adenovirus that evades neutralizing antibodies and shows improved anti-glioma efficacy in mice.

This study shows that combining fedratinib and venetoclax effectively kills B-ALL cells with high FLT3 expression, both in vitro and in vivo.

This study shows that CISD3 deficiency in mice causes muscle atrophy and mitochondrial dysfunction, revealing its role in Complex I function and muscle maintenance.

This study demonstrates that MinION-only sequencing can accurately assemble giant virus genomes, enabling rapid genome-wide analysis of newly isolated viruses.

The paper identifies a metabolic vulnerability in specific glioma cell states that can be targeted with GPX4 inhibitors to induce ferroptosis.

This study shows that multifactorial stress combinations negatively affect rice and maize growth, with proteomics revealing common stress-responsive proteins.

This study identifies Aphyd as an ER membrane protein that regulates both fission and fusion machinery recruitment to ER-mitochondria contact sites by altering phospholipid composition.

This study identifies H2BFWT's role in spermatogenesis by showing its impact on nucleosome stability and gene expression through structural and functional analyses.

This paper shows that adaptive immunity enhances the durability of alectinib response in EML4-ALK lung cancer models, with CD8+ T cells playing a key role.

This study demonstrates that magnetic torque-driven motion enhances infiltration of living microrobots across physiological barriers both in vitro and in vivo.

This study identifies liver stem cells as targets of HCV infection, showing their transcriptional reprogramming and role in liver damage and cancer risk.

This study evaluates the immune response and safety of the protein subunit vaccine Nanocovax in animal models, showing high immunogenicity and no adverse effects.

This study uses mass spectrometry imaging to visualize cholesterol distribution in mouse brain tissue, showing reduced cholesterol in specific regions of NPC1 disease models and during development.

This study uses mitochondrial genomes to reconstruct the evolutionary history of Carnivora, identifying divergence times and resolving phylogenetic relationships among major groups.

This study uses directed evolution to reengineer the BoNT/A protease to target SNAP23, improving its cleavage specificity and catalytic efficiency for therapeutic applications.

This study evaluates the safety and efficacy of chemo-attenuated Plasmodium falciparum immunization, identifying immune signatures that correlate with vaccine protection.

This study identifies an Acinetobacter baumannii isolate with ISAba3-blaOXA-58 gene structure that overexpresses blaOXA-58, leading to imipenem resistance and high periplasmic beta-lactamase activity.

The paper develops a data-driven method to deconvolute bulk tumor transcriptomes and predict cancer-stromal crosstalk in 20 solid tumor types, revealing new insights into signaling patterns.

The paper shows that aPKC isoforms sustain HH signaling and BCC growth without primary cilia by compensating for ciliary loss in advanced cancers.

The paper models SHR-SCR complex stoichiometry and regulation to explain differences in division timing between QC and CEI in Arabidopsis root stem cells.

This study identifies HAI1-regulated phosphorylation sites in Arabidopsis, showing AHL10 S314 phosphorylation controls growth and stress responses.

This study shows that antibiotic-induced dysbiosis predicts mortality in a C. difficile infection model using hamsters.

The paper uses citizen-science data to analyze human stool microbiomes, revealing new insights into microbial diversity, metabolome composition, and associations with diet and health.