Author

N. Mabe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

B. Englinger· 1 shared B. Shim· 1 shared C.-C. Lin· 1 shared D. Jeong· 1 shared D. L. Mayhew· 1 shared E. A. Panditharatna· 1 shared H. Justin· 1 shared J. Alvarez· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

B. Englinger

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2 papers

Recent·Most cited

VRK1 is required in VRK2-methylated cancers of the nervous system

J. So, N. Mabe, B. Englinger, M. Trissal, D. Jeong, E. A. Panditharatna, J. G. Marques, H. Justin, J. Kwon, S. M. Moyer, B. Shim, D. L. Mayhew, K. Stegmaier, M. G. Filbin, W. C. Hahn

The paper identifies VRK1 as a synthetic lethal target in VRK2-methylated nervous system cancers through CRISPR screens and functional studies.

bioRxiv · Dec 28, 2021 · PreprintCancer Biology

RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence

C.-C. Lin, N. Mabe, Y.-T. Lin, W.-H. Yang, X. Tang, L. Hong, T. Sun, T.-P. Yao, J. Alvarez, J.-T. Chi

This study identifies RIPK3 upregulation in recurrent breast tumors, showing it promotes proliferation but also creates dependence on cystine, offering new therapeutic targets.

bioRxiv · Jun 21, 2019Cancer Biology