Author

N. Manzar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1

Frequent Co-Authors

B. Ateeq· 3 shared N. Gupta· 2 shared N. Palanisamy· 2 shared S. Carskadon· 2 shared A. Bajpai· 1 shared A. Goel· 1 shared A. Thakur· 1 shared A. Yadav· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCancer Biology

B. Ateeq

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Author profile →

3 papers

Recent·Most cited

An integrative proteomics approach identifies tyrosine kinase KIT as a novel therapeutic target for SPINK1-positive prostate cancer.

N. Manzar, U. K. Khan, A. Goel, S. Carskadon, N. Gupta, N. Palanisamy, B. Ateeq

The paper identifies KIT as a therapeutic target for SPINK1-positive prostate cancer through integrative proteomics and shows KIT inhibition reduces tumor growth and metastasis.

bioRxiv · Jul 24, 2023Cancer Biology

A Drosophila model of oral peptide therapeutics for adult intestinal stem cell tumors

A. Bajpai, Q. T. Ahmad, H.-W. Hong-Wen Tang, N. Manzar, V. Singh, A. Thakur, B. Ateeq, N. Perrimon, P. Sinha

This paper evaluates the efficacy of a TONDU peptide in suppressing Yki-driven intestinal stem cell tumors in Drosophila by inhibiting YAP-TEAD interaction and modulating integrin signaling.

bioRxiv · Jan 21, 2020Cancer Biology

Androgen deprivation upregulates SPINK1 expression and potentiates cellular plasticity in prostate cancer

R. Tiwari, N. Manzar, V. Bhatia, A. Yadav, S. Carskadon, N. Gupta, A. Zoubeidi, N. Palanisamy, B. Ateeq

This study shows that androgen deprivation therapy upregulates SPINK1, which enhances cellular plasticity and contributes to poor outcomes in prostate cancer.

bioRxiv · Feb 27, 2019Cancer Biology