An integrative proteomics approach identifies tyrosine kinase KIT as a novel therapeutic target for SPINK1-positive prostate cancer.
N. Manzar, U. K. Khan, A. Goel, S. Carskadon, N. Gupta, N. Palanisamy, B. Ateeq
The paper identifies KIT as a therapeutic target for SPINK1-positive prostate cancer through integrative proteomics and shows KIT inhibition reduces tumor growth and metastasis.
bioRxiv · Jul 24, 2023Cancer Biology