N. Martino

The paper investigates how shock-induced IL-6 signaling alters DNA methylation and transcription in endothelial cells, revealing a mechanism for sustained vascular dysfunction post-shock.

This paper introduces multi-pass flow cytometry using laser particle barcoding to enable high-dimensional single-cell analysis with reduced spectral overlap and simplified panel design.

The paper shows that sIL-6R enhances LPS-induced endothelial dysfunction by activating STAT1/STAT3, which is blocked by SOCS3 overexpression or JAK inhibition.

This paper shows that endothelial SOCS3 prevents shock-induced organ failure by inhibiting IL-6 signaling and maintaining vascular barrier function.

This paper introduces laser particles for multiplexed cell tagging and imaging, demonstrating their stability, biocompatibility, and ability to track individual cells in 3D tumor models.