Author

N. Nuechterlein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

E. C. Holland· 2 shared F. Szulzewsky· 2 shared J. Shendure· 2 shared P. J. Cimino· 2 shared S. Arora· 2 shared A. J. Patel· 1 shared C. A. Parada· 1 shared C. Qiu· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

E. C. Holland

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2 papers

Recent·Most cited

Meningioma transcriptomic landscape demonstrates novel subtypes with regional associated biology and patient outcome.

H. N. Thirimanne, D. A. Bonnin, N. Nuechterlein, S. Arora, M. Jensen, C. A. Parada, C. Qiu, F. Szulzewsky, C. W. English, W. C. Chen, P. Sievers, F. Nassiri, J. Z. Wang, T. J. Klisch, K. D. Aldape, , E. C. Holland

This study combines bulk RNA-Seq datasets to create a transcriptomic landscape of meningiomas, identifies subtypes with distinct biology and prognosis, and provides an interactive tool for outcome prediction.

bioRxiv · Feb 23, 2024Cancer Biology

Oncogenic role of a developmentally regulated NTRK2 splice variant

S. S. Pattwell, S. Arora, N. Nuechterlein, M. Zager, K. R. Loeb, P. J. Cimino, N. C. Holland, N. Reche-Ley, H. Bolouri, D. A. A. Bonin, F. Szulzewsky, V. V. Phadnis, T. Ozawa, M. J. Wagner, M. C. Haffner, , E. C. Holland

The paper identifies TrkB.T1, an embryonic NTRK2 splice variant, as an oncogenic driver in multiple tumor types across species, with distinct interactors in developmental and oncogenic pathways.

bioRxiv · Jan 7, 2022 · PreprintCancer Biology