Cancer BiologybioRxivPreprint
Oncogenic role of a developmentally regulated NTRK2 splice variant
S. S. Pattwell, S. Arora, N. Nuechterlein…·E. C. Holland
The paper identifies TrkB.T1, an embryonic NTRK2 splice variant, as an oncogenic driver in multiple tumor types across species, with distinct interactors in developmental and oncogenic pathways.