E. C. Holland

This study uses in vitro evolution of commensal Neisseria species to investigate resistance evolution to azithromycin and penicillin, finding convergent mutations in key resistance mechanisms.

This study modifies the CUTAC protocol to enable high-resolution epigenomic analysis of FFPE samples, identifying regulatory element differences in mouse brain tumors.

This study shows that YAP1-MAML2 and active YAP1 drive tumors resembling NF2-mutant meningiomas in mice through TEAD-dependent YAP activity.

The paper identifies TrkB.T1, an embryonic NTRK2 splice variant, as an oncogenic driver in multiple tumor types across species, with distinct interactors in developmental and oncogenic pathways.

This study uses single-cell RNA sequencing to analyze immune cell changes during glioma progression, identifying immunosuppressive myeloid cell subsets and potential therapeutic targets.