Cell BiologybioRxivPreprint
Hypoxia shapes the immune landscape in lung injury promoting inflammation persistence
A. S. Mirchandani, S. J. Jenkins, C. C. Bain…·S. Walmsley
This study shows hypoxia suppresses type I interferon signaling in ALI, leading to monocytopenia and unchecked inflammation, which can be mitigated by CSF1 administration.
DOI 10.1101/2022.03.11.483935