ImmunologybioRxivPreprint
The Identification of IL-4 as a Regulator of Chimeric Antigen Receptor T Cell Exhaustion
C. M. Stewart, E. L. Siegler, R. L. Sakemura…·S. S. Kenderian
This study identifies IL-4 as a regulator of CART cell exhaustion and shows that IL-4 neutralization improves antitumor efficacy.