Author

N. Schubert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Roers· 2 shared R. Behrendt· 2 shared A. Gerbaulet· 1 shared B. Utess· 1 shared C. M. Hill· 1 shared C. Tun· 1 shared E. D. Dar· 1 shared E. Marinkovic· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

A. Roers

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2 papers

Recent·Most cited

Selective inflammation of the tumor microenvironment and invigorated T cell-mediated tumor control upon induced systemic inactivation of TREX1

E. Marinkovic, M. Chen, N. Schubert, E. D. Dar, J. Y. Leung, J. Lohre, J. M. Sahni, C. Tun, P. Rajeswaran, T. Mehlo-Jensen, O. A. Perng, C. M. Hill, P. V. Sivakumar, M. J. Barnes, R. Malik, , A. Roers

This study shows that systemic TREX1 inhibition enhances anti-tumor immunity by increasing T cell infiltration and activity in tumors while sparing other tissues.

bioRxiv · Jun 9, 2024 · PreprintImmunology

cGAS/STING-DEPENDENT SENSING OF ENDOGENOUS RNA

T. Schumann, S. C. Ramon, N. Schubert, M. A. Mayo, M. Hega, S.-R. Ada, L. Sydow, M. Hajikazemi, Y. Ge, M. Badstübner, S. Lienenklaus, B. Utess, L. Muhandes, M. Haase, L. Müller, , R. Behrendt

The paper shows that loss of SAMHD1 leads to chronic DNA damage and cGAS/STING-dependent type I interferon production in mice, linking it to autoimmunity and cancer.

bioRxiv · May 16, 2022Immunology