ImmunologyFrontiers in ImmunologyPeer-reviewed
Precision engineering of an anti-HLA-A2 chimeric antigen receptor in regulatory T cells for transplant immune tolerance
Y. D. Muller, L. M. R. Ferreira, E. Ronin…·Q. Tang
This paper develops an anti-HLA-A2 CAR for Tregs to induce transplant tolerance, showing they target HLA-A2-expressing grafts and suppress immune rejection.
DOI 10.3389/fimmu.2021.686439