Author

S. Omo-Lamai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

J. Nong· 3 shared J. S. Brenner· 3 shared J. W. Myerson· 3 shared O. A. Marcos-Contreras· 3 shared D. Weissman· 2 shared M. E. Zamora· 2 shared P. M. Glassman· 2 shared R. Y. Kiseleva· 2 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersPharmacology & Toxicology

J. Nong

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3 papers

Recent·Most cited

BioengineeringbioRxivJul 21, 2023

Physicochemical Targeting of Lipid Nanoparticles to the Lungs Induces Clotting: Mechanisms and Solutions

S. Omo-Lamai, M. E. Zamora, M. N. Patel…·J. S. Brenner

This study identifies thrombosis as a risk of lung-targeted cationic lipid nanoparticles and proposes solutions to mitigate clotting without compromising targeting.

DOI 10.1002/adma.202312026

experimental assaymechanistic / dynamical model

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivJun 12, 2023

Targeting lipid nanoparticles to the blood brain barrier to ameliorate acute ischemic stroke

J. Nong, P. M. Glassman, S. Reyes-Esteves…·O. A. Marcos-Contreras

This paper develops VCAM-targeted lipid nanoparticles to enhance drug delivery to the blood-brain barrier in acute ischemic stroke, reducing infarct volume and mortality.

DOI 10.1016/j.ymthe.2024.03.004

mouseexperimental assay

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivPreprintFeb 4, 2022

Targeted nanocarriers coopting pulmonary leukocytes for drug delivery to the injured brain

P. M. Glassman, J. Nong, J. W. Myerson…·O. A. Marcos-Contreras

This paper demonstrates a strategy for targeted drug delivery to the injured brain by loading drugs onto pulmonary leukocytes using ICAM-targeting nanocarriers, showing increased brain uptake and therapeutic effect in a mouse model.

DOI 10.1101/2022.02.04.479150

mouseexperimental assay

𝕏 PostBluesky