Author

O. Garwain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1 Organism:rat· 1

Frequent Co-Authors

L. Jackson· 2 shared A. Qifti· 1 shared A. Singla· 1 shared B. Rosati· 1 shared D. R. Iyer· 1 shared K. M. Pearce· 1 shared L. J. Zhu· 1 shared P. D. Kaufman· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBiochemistry

L. Jackson

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Stimulation of phospholipase Cβ1 by Gαq promotes the assembly of stress granule proteins

A. Qifti, L. Jackson, A. Singla, O. Garwain, S. Scarlata

This study shows that Gαq activation promotes stress granule formation via cytosolic PLCβ1, leading to the assembly of stress granule proteins.

bioRxiv · Sep 26, 2021 · PreprintBiochemistry

The chromatin-binding domain of Ki-67 together with p53 protects human chromosomes from mitotic damage

O. Garwain, X. Sun, D. R. Iyer, R. Li, L. J. Zhu, P. D. Kaufman

This study shows that the C-terminal chromatin-binding domain of Ki-67, along with p53, prevents mitotic chromosome damage in human cells.

bioRxiv · Oct 16, 2020Cell Biology

Simulation of the Gαq /Phospholipase Cβ1 Signaling Pathway Returns Differentiated PC12 Cells to a Stem-like State

O. Garwain, K. M. Pearce, L. Jackson, S. Carley, B. Rosati, S. S. Scarlata

The paper shows that reducing PLCβ1 or activating Gq to move PLCβ1 to the plasma membrane reverts differentiated PC12 cells to a stem-like state, characterized by morphology changes, proliferation, and expression of stem cell factors.

bioRxiv · Jan 6, 2020 · PreprintBiochemistry