D. R. Iyer

This study shows that aneuploidy can trigger chromosome instability (CIN) by causing DNA replication stress and continuous CIN, leading to genetically diverse cells with varying proliferation abilities.

This study shows that the C-terminal chromatin-binding domain of Ki-67, along with p53, prevents mitotic chromosome damage in human cells.

This paper investigates how DNA damage affects replication fork behavior in fission yeast, finding that the intra-S checkpoint slows replication by inhibiting origin firing but not fork speed, and facilitates lesion bypass while preventing fork stalling.